Posted by: arisfil | February 3, 2008

Hydrocephalus Debate

Cerebrospinal Fluid Research 

A debate has started by a leader in pediatric neurosurgery, Dr Harold Rekate. Dr Rekate submitted an article in open access journal “Cerebrospinal Fluid Research”, concerning Hydrocephalus and its definition. It was published in 22th of January 2008. He outlines the history of its definition form through literature and proposes a new definition consensus. He states that “hydrocephalus is an active distension of the ventricular system of the brain resulting from inadequate passage of cerebrospinal fluid from its point of production within the cerebral ventricles to its point of absorption into the systemic circulation.” He also notes that the lack of agreement in hydrocephalus definition has impeded the progression of research to the field. This provisional article presents the theories and experience of Dr Rekate with quality schematics of flow system of the CSF.

Is it time to reconsider the definition of Hydrocephalus ?

The sure thing is that it is the time for the scientific community to consent to a working definition.

The article content (PDF) is under Dr Rekate’s copyright and distributed under Open Access initiative.

reference: Cerebrospinal Fluid Res. 2008 Jan 22;5(1):2 [Epub ahead of print]

 

GOOGLE GROUPS Encephalos Discussion Thread: click

 

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Responses

  1. ok

  2. Why would lack of a consensus on a definition impede research? It really is kind of outrageous that hydrocephalus has been treated primarily with shunts for 50 years, and very little has been done to find out the cause, discover new treatments, or deal with the million life issues that people with hydrocephalus face. (My son, now 42, was born with hydro).

  3. Well, a lack of consensus about the definition of hydrocephalus impedes research in the way that hydrocephalus seems to has a lot of causes that various definitions have to include. For example: For a lot of years we use the terms “communicating” and “non-communicating” hydrocephalus. These terms represent an non-obstruction or obstruction in the ventricular system but we should not think only of obstruction when we talk about hydrocephalus. For example, recent research has identified additional causes like dysfunctional ependymal cilia that may be genetically controlled (see link below)
    (http://dev.biologists.org/cgi/content/abstract/132/23/5329?maxtoshow=&HITS=&hits=&RESULTFORMAT=&fulltext=hydrocephalus+cilia&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&resourcetype=HWCIT)

    So various definitions and categories should be implemented in hydrocephalus research in order to communicate better among the scientific community and the patients. We have to know about what exactly we are talking in order to conduct high quality research.

  4. Might also be of interest:

    Learning disabilities in children with hydrocephalus
    http://www.encephalos.gr/45-1-06e.htm


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