Posted by: arisfil | February 6, 2008

Suicide and antiepileptics

Edouard Manet Edouard Manet, Suicide, 1877  

(at Sammlung E. G. Bührle, Zürich)

FDA this month issued a warning about increased suicidality in patients using antiepileptic drugs (AEDs). They analysed 199 placebo-controlled trials concerning 11 antiepileptic drugs. They searched for patients demonstrating suicidal behavior or suicidal ideation in a sample of 43,892 antiepileptic drug users. The conclusion was that patients on AEDs showed a significantlly increased suicidal behavior or ideation comparing to placebo! We should mention that 4 suicides where committed in this group.

If you would like to report an AED adverse effect you should go to http://www.fda.gov/medwatch 

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