Posted by: arisfil | February 19, 2008

Chronic pain may harm brain function

 fMRI fMRI, image from Wikipedia

Individuals with chronic back pain demonstrated altered functional connectivity to cortical brain areas unrelated to pain comparing to healthy individuals. This conclusion is described in a research article published by Dr Chialvo’s team at the February 6th issue of the Journal of Neuroscience. The researchers studied the alterations of brain’s Default Mode Network (DMN) using fMRI in patients with chronic pain and controls. DMN is an assembly of brain regions responsible for the “resting phase” of brain. These regions “shut off” when brain is accomplishing a task. The team from Northwestern University found that in individuals with chronic pain this DMN is never “shut off” but it is rather “silenced”. This altered function of DMN can hurt the brain regions involved.

Comment: 

These findings are leading in the interpretation of pain perception and its long term effects to brain regions. It is a well orchestrated research, unveiling data that could not be otherwise studied without the utilization of fMRI.

 The Journal of Neuroscience, February 6, 2008, 28(6):1398-1403

 copyright © 2008 by the Society For Neuroscience

 

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Responses

  1. […] Chronic pain may harm brain functionThe researchers studied the alterations of brain’s Default Mode Network (DMN) using fMRI in patients with chronic pain and controls. DMN is an assembly of brain regions responsible for the “resting phase” of brain. … […]


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